Friday, January 21, 2022

So you are sick with Omicron. When do you need a COVID-19 booster injection?

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In a matter of weeks, hundreds of thousands of Canadians may have been infected with the Omicron variant of the coronavirus.

An unprecedented increase in cases has led to the cancellation of surgeries, a shortage of staff in the health care system and a record increase in hospitalizations – many less serious diseases, including those fully vaccinated against COVID-19 between

If you’re one of those who is now getting an increased number of infections after vaccination, the question may arise as to when to get an amplifier – or whether you need it at all.

“People still need to get stronger,” Dr. Linora Sakinger, an infectious disease specialist and associate professor at the University of Alberta in Edmonton, told the News. “I think the hardest, when is the best time to increase strength?”

Regional guidelines for this time vary across the country, from Quebec’s offer to wait until your symptoms disappear, to the recommendation of Ontario’s best doctor to hold it for 30 days.

There are no magic numbers, but the science of how our immune system works means that you can expect to use a booster for weeks or even months after an Omicron infection.

SEE | Mixed recommendations for setting amplifier time after Omicron recovery:

Mixed recommendations on amplifier time after Omicron recovery

People who have recovered from the Omicron option are hearing a variety of tips on when to take a COVID-19 booster shot soon after recovery or a few weeks later. 2:02

Do not inject when you are sick

In general, if you’re sick, you can’t get any kind of vaccine, said Alison Kelvin, a virologist and vaccine researcher at the University of Saskatchewan’s Vaccine and Infectious Diseases Organization in Saskatoon.

“Whatever your body is fighting, your immunity will be focused on that pathogen,” he explained.

However, your body may not respond as effectively to a dose of vaccine designed to trigger your immunity, mimicking a threat like a coronavirus. “So, in general, we have to wait a while after infection to get any vaccine,” Kelvin said.

According to him, the ideal time to take an invigorating shot is when your immunity has calmed down.

Kelvin likened what happens in your body to the process of hiring people: You want highly qualified candidates for a specific position, which in this case means fighting coronavirus.

“Let’s say you’re posting a job and a lot of people are responding to that job. It’s when you are first vaccinated or you’re infected and your immunity starts to attract all of that. Immune cells,” he said.

It’s a busy time, but the bulk of these immune cells – or job applicants, let’s say – will eventually run out. That’s when you want to have another power to restart your immune system or, like Kelvin, another chance to regroup with the most suitable applicants for the job.

“So you want to wait until the symptoms go away and it will be helpful to wait an extra month or a few weeks after your first infection because you will benefit more from this exacerbation,” he said.

There is no need to rush to take a booster after an infection

Other immunologists agreed that there was no urgent need for a booster after infection.

“I think it’s better to wait a few months before boosting, because then boosting will be more effective,” said Dr. Jamie Scott, a molecular immunologist and honorary professor at Simon Fraser University in Burnaby, BC. ‘is a mystery because memory cells develop more fully and antibody levels decrease.

Dipta Bhattacharya, a professor of immunobiology at the University of Arizona in Tucson, said, “I don’t think it makes sense to get an amplifier soon after you’ve recovered from an omicron infection.”

Preliminary data Infections with this option also protect against infection with the Delta variant, which was once dominant, he said, which reduces the likelihood of instantly infecting any version of your virus.

And as Bhattacharya points out, not rushing and getting an amplifier as soon as you recover is consistent with Canada’s unconventional vaccination approach during the pandemic – dose separation.

Canada is famous for its dose range

Prior to the shipment of vaccines, the National Immunization Advisory Committee of Canada made bold recommendations to delay the second dose by four months, far beyond the production guidelines.

Although the move was controversial at the time, vaccine experts told the News that it had been based on vaccine science for decades and can actually provide more protection rather than following a strict schedule of clinical trials.

“One of the things Canada has taught us is that separating them from each other – separating the exposure time – makes a big difference in the quality and size of the antibodies you get,” Bhattacharya said.

The next step in protecting people from Omicron and future options may require the development of vaccines tailored to these threats.

“The amplifiers we have now are compatible with a strain that has already passed and will probably never be seen again,” he said. “So I hope we have better options along the way.”

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